Herbert Oberacher, Ph.D.
Institute of Legal Medicine
Innsbruck Medical University
Muellerstrasse 44
6020 Innsbruck
Austria

Email: herbert.oberacher@i-med.ac.at

Herbert Oberacher is an analytical chemist. In 2002 he received his PhD at the University of Innsbruck, Austria. After spending a year as postdoctoral fellow at the University of the Saarland, Germany, he got a position at the Institute of Legal Medicine of the Innsbruck Medical University, Austria. In 2007 he received the “venia docendi” for bioanalysis. His research focuses on the development of mass spectrometric techniques for the analysis of bioorganic molecules with special emphasis on nucleic acids. For this research, he received several awards: Fachgruppenpreis der Fachgruppe Analytische Chemie of the German Chemical Society (2003), Adolf Martens Award (2006), Austrian Life Science Award (2006), and the Mattauch Herzog Award of the German Society for Mass Spectrometry (2008). He has (co-)authored more than 40 papers in international scientific journals, and holds two patents.

Selected Publications

Oberacher, H.
On the Use of Different Mass Spectrometric Techniques for the Characterization of Sequence Variability in Genomic DNA.
Analytical and Bioanalytical Chemistry, 391 (2008), 135-149.

Oberacher, H., Pitterl, F., Huber, G., Niederstätter, H., Steinlechner, M., Parson, W.
Increased Forensic Efficiency of DNA Fingerprints through Simultaneous Resolution of Length and Nucleotide Variability by High-Performance Mass Spectrometry.
Human Mutation, 29 (2008), 427-432.

Oberacher, H., Niederstätter, H., Parson, W.
Liquid Chromatography–Electrospray Ionization Mass Spectrometry for Simultaneous Detection of mtDNA Length and Nucleotide Polymorphisms.
International Journal of Legal Medicine, 121 (2007), 57-67.

Oberacher, H., Niederstätter, H., Pitterl, F., Parson, W.
Profiling 627 Mitochondrial Nucleotides via the Analysis of a 23-plex Polymerase Chain Reaction by Liquid Chromatography-Electrospray Ionization Time-of-Flight Mass Spectrometry.
Analytical Chemistry, 78 (2006), 7816-7827.

Oberacher, H., Pitterl, F., Niederstätter, H., Weiss, E. M., Stadlmann, E., Marksteiner, J., Parson, W.
Direct Molecular Haplotyping of Multiple Polymorphisms within Exon 4 of the Human Catechol-O-Methyltransferase Gene by Liquid Chromatography-Electrospray Ionization Time-of-Flight Mass Spectrometry.
Analytical and Bioanalytical Chemistry, 386 (2006), 83-91.

Oberacher, H., Niederstätter, H., Huber, C. G., Parson, W.
Accurate Determination of Allelic Frequencies in Mitochondrial DNA Mixtures by Electrospray Ionization Time-of-Flight Mass Spectrometry.
Analytical and Bioanalytical Chemistry, 384 (2006) 1155-1163.

Oberacher, H., Niederstätter, H., Casetta, B., Parson, W.
Some Guidelines for the Analysis of Genomic DNA by PCR-LC-ESI-MS.
Journal of the American Society for Mass Spectrometry, 17 (2006) 124-129.

Oberacher, H., Niederstätter, H., Casetta, B., Parson, W.
Detection of DNA Sequence Variations in Homo- and Heterozygous Samples via Accurate Molecular Mass Measurements with Electrospray Ionization Time-of-Flight Mass Spectrometry.
Analytical Chemistry, 77 (2005), 4999-5008.

Oberacher, H., Huber, C. G., Oefner, P. J.
Mutation Sreening by Ion-Pair Reversed-Phase High-Performance Liquid Chromatography - Electrospray Ionization Mass Spectrometry (ICEMS).
Human Mutation, 21 (2003), 86-95.

Oberacher, H., Oefner, P. J., Hölzl, G., Premstaller, A., Davis, K., Huber, C. G.
Re-Sequencing of Multiple Single Nucleotide Polymorphisms by Liquid Chromatography-Electrospray Ionization Mass Spectrometry.
Nucleic Acids Research 30 (2002) e67.

Huber, C. G., Oberacher, H.
Analysis of Nucleic Acids by On-Line Liquid Chromatography-Electrospray Ionization Mass Spectrometry.
Mass Spectrometry Reviews, 20 (2001) 310-343.

Oberacher, H., Oefner, P. J., Parson, W., Huber, C. G.*
On-Line Flüssigkeitschromatographie-Massenspektrometrie: Ein nützliches Werkzeug zur Detektion von Variationen in DNA Sequenzen.
Angewandte Chemie, 113 (2001) 3945-3948.