Bio: Paul T Spellman Ph.D.
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Education
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2000
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Stanford University Medical School, Ph.D. Genetics
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1995
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Massachusetts Institute of Technology, S.B. Biology
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Positions
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2000 – 2003
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Post-doctoral Fellow, UC Berkeley, Department of Mol. and Cell.Biology
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2007 – present
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Staff Scientist, Lawrence Berkeley Lab, Life Science Division
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2003 – 2007
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Scientist, Lawrence Berkeley Lab, Life Science Division
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Awards and Other Professional Activities
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2000 - 2001
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NSF Biocomputing Post-doctoral Fellowship
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2002
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Ad Hoc member, NSF, GEN-EN panel
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2002 - present
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Board member, Microarray Gene Expression Data Society
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2002 – 2006
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Treasurer, Microarray Gene Expression Data Society
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2005
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Ad Hoc member, EPA, Center for Bioinformatics Panel
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2006 & 2007
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Panel member, NIH/NHLBI, Exploratory Program in Systems Biology
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2007 – 2008
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International Cancer Genomics Consortium, scientific planning and data working group
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2008
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Welcome Trust Cancer Genome Sequencing Project External Advisory Board
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Selected Publications
P.T. Spellman, G. Sherlock, M. Q. Zhang, et al. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Molecular Biology of the Cell 9: 3273-97, 1998.
M. B. Eisen, P.T. Spellman, P. O. Brown and D. Botstein. Cluster analysis and display of genome-wide expression patterns. Proceedings of the National Academy of Sciences, U.S.A. 95: 14863-8, 1998.
G. Zhu, P.T. Spellman, T. Volpe, et al. Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth. Nature 406: 90-4, 2000.
A. P. Gasch, P. T. Spellman, C. M. Kao, et al. Genomic expression programs in the response of yeast cells to environmental changes. Molecular Biology of the Cell 11: 4241-57, 2000.
P. T. Spellman. The future of publishing microarray data. Briefings in Bioinformatics 2: 316-8, 2001.
E. De Gregorio, P. T. Spellman, G. M. Rubin and B. Lemaitre. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proceedings of the National Academy of Sciences, U.S.A. 98: 12590-5, 2001.
P. T. Spellman and G. M. Rubin. Evidence for large domains of similarly expressed genes in the Drosophila genome. Journal of Biology 1: 5, 2002.
P. T. Spellman, M. Miller, J. Stewart, C. et al. Design and implementation of microarray gene expression markup language (MAGE-ML). Genome Biology 3: RESEARCH0046, 2002.
E. De Gregorio, P. T. Spellman, P. Tzou, G. M. Rubin and B. Lemaitre. The Toll and Imd pathways are the
P. T. Spellman and G. Sherlock. Final words: cell age and cell cycle are unlinked. Trends Biotechnology. 6: 270-3, 2004.
P. T. Spellman and G. Sherlock. Reply: whole-culture synchronization – effective tools for cell cycle studies. Trends Biotechnology. 6: 277-8, 2004.
S. Brun, S. Vidal, P. Spellman, et al. The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila. Genes Cells 11:397-407, 2006
K. Chin K, S. DeVries, J. Fridlyand, et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 6:529-41. 2006
R.M. Neve, K. Chin, J. Fridlyand, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 6:515-27. 2006
T.F. Rayner, P. Rocca-Serra, P.T. Spellman, et al simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB. BMC Bioinformatics. 7:489. 2006
Y. Wang, M. Moorhead, G. Karlin-Neumann, et al. Performance of Molecular Inversion Probes (MIP) in Allele Copy Number Determination. Genome Biology. 8:R246. 2007
P.T. Spellman, J.F. Costello, J.W. Gray. Molecular Basis of Cancer, Mendelsohn J., Ed., Elsevier. 2008
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