Overview
- Introduction to HCA, instrument platforms and Experimental Study Design
- Reagents/Assay Development and Validation
- Image Analysis and Data Processing
- Bioinformatics for HCA/HCS
- Detection Methodologies and Monitoring
- Biological and Mechanistic Validation of HCA/HCS data
- Genomic Perturbations and Integration of HCA results with other data types
Day by Day
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Day 1: WEDS Nov 12
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7.30 am
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REGISTRATION
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Atrium |
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8.30 am
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Opening Ceremony
(1) Opening Speech by Conference Chairman
- Dr. Christopher Wong
(2) Welcome Speech by HUGO President
- Prof. Edison Liu
(3) Opening Keynote Address by BMRC Chairman, Sir David Lane, Ph.D.
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Padang |
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9.35 am
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TEA BREAK
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Foyer |
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10.05 am
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(I) INTRODUCTION TO HCA/HCS by Horst Flotow, Ph.D.
High Content Screening: Biologically relevant high throughput screening for drug discovery
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Padang |
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10.40 am
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(I) INTRODUCTION TO HCA/HCS by Eberhard Krausz, Ph.D.
Academic Screening Facilities at the Interface of Academia and Industry
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Padang |
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11.20 am
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(II) DETECTION METHODOLOGIES & MONITORING by O. Joseph Trask, Jr., Ph.D.
The Past, Present, and Future of High Content Screening
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Padang |
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12.05 pm
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(II) DETECTION METHODOLOGIES & MONITORING by Michael Boutros, Ph.D.
Functional Segmentation of the Genome by Quantitative Phenotypic Analysis using RNAi
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Padang |
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12.50 pm
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OPENING OF EXHIBITION HALL / POSTER SESSION
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Canning |
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12.50 pm
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TECHNICAL LUNCH TALK
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(1) MDS ANALYTICAL TECHNOLOGIES / RESEARCH INSTRUMENTS
High Content Assay Development and Screening with ImageXpress® and Isocyte® Imaging Systems
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Moor |
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(2) FLUIDIGM
Deciphering the Preimplantation Developmental Regulatory Network at the Single Cell Level
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Padang |
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2.15 pm
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(III) REAGENTS / ASSAY DEVELOPMENT / VALIDATION by Peter O’Brien, Ph.D.
High Content Analysis for Potential, Mechanism and Biomarkers for Human Toxicity
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Padang |
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3.00 pm
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PLATFORM DEMONSTRATION
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(1) MDS / Research Instruments
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Blundell |
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(2) GE Healthcare
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Butterworth |
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(3) BD Biosciences
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Bonham |
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(4) Thermo Scientific Cellomics
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Fullerton |
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3.00 pm
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(III) REAGENTS / ASSAY DEVELOPMENT / VALIDATION by William Chun Hahn, Ph.D.
High throughput screening with a lentivirally delivered shRNA library
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Padang
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3.45 pm
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(IV) INTRODUCTION TO BIOINFORMATICS by Mark Collins, Ph.D.
The Human Cellome – Math, Magic or Reality?
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Padang |
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| 4.30 pm |
TEA BREAK
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Canning |
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4.50 pm
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(IV) INTRODUCTION TO BIOINFORMATICS by Vance Lemmon, Ph.D.
Validation and Visualization of Data from Phenotypic Screens of Primary Neurons
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Padang |
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5.25 pm
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(IV) INTRODUCTION TO BIOINFORMATICS by Anne Carpenter, Ph.D.
Quantifying complex and subtle phenotypes in images for high content screening
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Padang |
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| 6.15 pm |
POSTER SESSION
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Foyer |
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7.30 pm
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DINNER KEYNOTE by D Lansing Taylor, Ph.D.
The Continuing Evolution of High Content Screening
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Padang |
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8.10 pm
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COMMENCEMENT OF DINNER
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Padang |
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| Day 2: THURS NOV 13 |
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7.30 - 8.30 am
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REGISTRATION / LIGHT REFRESHMENT @ CANNING
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Atrium |
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| 8.30 pm |
PLATFORM DEMONSTRATION
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(1) MDS / Research Instruments
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Blundell |
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(2) GE Healthcare
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Butterworth |
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(3) BD Biosciences
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Bonham |
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(4) Thermo Scientific Cellomics
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Fullerton |
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8.30 am
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(V) REAGENTS / ASSAY DEVELOPMENT II by Chang Young-Tae, Ph.D.
Colorful Chemical Genetics
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Padang |
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9.15 am
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(V) REAGENTS / ASSAY DEVELOPMENT II by Vivek Abraham, Ph.D.
Development and Validation of Live Cell HCS Assays
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Padang |
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9.50 am
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(V) REAGENTS / ASSAY DEVELOPMENT II by Thomas Murphy, Ph.D.
A User’s Guide to the Design and Implementation of a HCS Experiment
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Padang |
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10.25 am
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TEA BREAK
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Canning |
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10.45 am
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(V) REAGENTS / ASSAY DEVELOPMENT II by Mike Ignatius, Ph.D.
Reagents for HCS based Tox Profiling from Molecular Probes
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Padang |
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11.25 am
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(V) ADVANCED BIOINFORMATICS by Stephan Schürer, Ph.D.
Chemoinformatics Approaches in High-Content Screening Data Analysis
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Padang |
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12.00 nn
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(V) ADVANCED BIOINFORMATICS by Frederic Bard, Ph.D.
A high content, functional genomics approach to the regulation of Golgi structure
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Padang |
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12.45 pm
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EXHIBITION / POSTER SESSION
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Canning / Foyer |
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TECHNICAL LUNCH TALK
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(1) ROCHE APPLIED SCIENCE
Identification of Mechanism of Drug Action and Potential Off-Target Drug Effects Using the xCELLigence System from Roche Applied Science
xCELLigence – Label-free, real-time cell monitoring technology
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Moor |
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(2) GE HEALTHCARE
IN Cell System, the High Content Analysis Technologies from GE Healthcare
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Padang |
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| 2.10 pm |
PLATFORM DEMONSTRATION
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(1) MDS / Research Instruments
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Blundell |
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(2) GE Healthcare
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Butterworth |
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(3) BD Biosciences
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Bonham |
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(4) Thermo Scientific Cellomics
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Fullerton |
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| 2.15 pm |
(VI) ADVANCED BIOINFORMATICS II by Caty Chung, M.S.
High Content Screening – from an informatics perspective
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Padang |
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2.50 pm
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(VI) ADVANCED BIOINFORMATICS II by Adam Szafran, Ph.D.
Androgen receptor functional analyses by high throughput systems biology
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Padang |
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3.25 pm
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TEA BREAK
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Canning |
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3.45 pm
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(VII) ADVANCED BIOINFORMATICS I by Yan Feng, Ph.D.
Integrating phenotypic profiles and affinity profiles of active compounds to draw mechanisms of action inferences
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Padang |
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4.20 pm
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(VII) ADVANCED BIOINFORMATICS I by Paul Spellman, Ph.D.
Development of Drug Response Predictors from In Vitro Systems
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Padang |
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4.55 pm
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(VII) ADVANCED BIOINFORMATICS I by Roderick Beijersbergen, Ph.D.
The RNAi strategy in Cancer Target Discovery and Validation
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Padang |
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6.30 pm
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COCKTAIL RECEPTION CUM POSTER SESSION
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Canning / Foyer |
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Day 3: FRI NOV 14
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7.30 am
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REGISTRATION / LIGHT REFRESHMENT @ CANNING
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Atrium |
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8.30 am
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(VIII) ASSAY MINIATURISATION / MULTIPLEXING by Namyong Kim, Ph.D.
DropArray™ Platform for Hassle-free Miniaturization and Multiplexing of High Content Assays
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Padang |
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9.05 am
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(VIII) ASSAY MINIATURISATION / MULTIPLEXING by Anthon Mitchell Davis, Ph.D.
Assay miniaturisation and multiplexing strategies
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Padang |
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10.20 am
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TEA BREAK
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Canning |
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10.40 am
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(IX) BIOLOGICAL AND MECHANISTIC VALIDATION OF HCA/HCS DATA by Robert Morris Campbell, Ph.D.
Application of high content imaging technologies for cancer research
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Padang |
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11.25 am
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(IX) BIOLOGICAL AND MECHANISTIC VALIDATION OF HCA/HCS DATA by William Adam Grandfield Hill, Ph.D.
High Throughput High Content Screening Compared with Single Readout HTSs -Lessons Learned to Date
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Padang |
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12.10 pm
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EXHIBITION / POSTER SESSION
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Canning / Foyer |
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TECHNICAL LUNCH TALK
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(1) BD BIOSCIENCES
High-Content Imaging – Emit More Data!
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Moor |
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(2) TIBCO SPOTFIRE® / RESEARCH INSTRUMENTS
Informed Decision Making in High Content Data Analysis
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Padang |
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1.40 pm
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(IX) BIOLOGICAL AND MECHANISTIC VALIDATION OF HCA/HCS DATA by Alexis Borisy, A.M.
Combination Chemical Genetics in Phenotypic Screens Identify Synergistic and Selective Therapies
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Padang |
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| 2.25 pm |
TEA BREAK
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Foyer |
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2.45 pm
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(X) CLOSING KEYNOTE by Sir Michael A White, Ph.D.
Towards Functional Annotation of the Cancer Genome
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Padang |
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3.30 pm
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(X) CLOSING KEYNOTE by William Chun Hahn, Ph.D.
Integrating functional and structural genomics to discover and validate cancer targets
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Padang |
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4.20 pm
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CLOSING OF WORKSHOP
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Padang |
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Demonstration
Specific-themed stations of high content screening and imaging platforms are set up together with bioinformatics analytical and computing systems for
hands-on and live demonstration.
Special slots are open for pre-signed up to ensure maximum exposure for participants.
Technical Talks
Interesting technical lunch talks are available for those who want to find out more about the technical development and application in HCA / HCS laboratories.
Meet the Expert Luncheon
Meet the Expert Luncheon provides an excellent opportunity and learning experience for small group networking with our prominent speakers and VIPs.
Pre-signed up is required upon registration to the event.
Posters
Posters accepted will be displayed at the venue through the event. Dedicated time slots will be reserved for oral presentation.
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